Cirrhosis occurs when hard scar tissue replaces soft healthy tissue in the liver. As the condition becomes worse the liver begins to fail. Other diseases that affect the liver tissue cause cirrhosis, including viral hepatitis, bile duct disease, genetic diseases and chronic alcoholism & non-alcoholic fatty liver disease related scarring.. Symptoms of cirrhosis include loss of appetite, fatigue, nausea, weight loss and abdominal pain, jaundice, easy brusing and abdominal distention.